Lack of Major Involvement of Common CYP2C Gene Polymorphisms in the Risk of Developing Cross-Hypersensitivity to NSAIDs

• Main Authors: Yolanda Macías (Author), Jesús M. García-Menaya (Author), Manuel Martí (Author), Concepción Cordobés (Author), Raquel Jurado-Escobar (Author), José A. Cornejo-García (Author), María J. Torres (Author), Natalia Blanca-López (Author), Gabriela Canto (Author), Miguel Blanca (Author), José J. Laguna (Author), Joan Bartra (Author), Ana Rosado (Author), Javier Fernández (Author), Elena García-Martín (Author), José A. G. Agúndez (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cross-hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) is a relatively common, non-allergic, adverse drug event triggered by two or more chemically unrelated NSAIDs. Current evidence point to COX-1 inhibition as one of the main factors in its etiopathogenesis. Evidence also suggest...