Antibody-siRNA conjugates (ARC): Emerging siRNA drug formulation

• Main Authors: Weiran Cao (Author), Rui Li (Author), Xing Pei (Author), Meihong Chai (Author), Lu Sun (Author), Yuanyu Huang (Author), Jiancheng Wang (Author), Stefan Barth (Author), Fei Yu (Author), Huining He (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antibody-drug conjugates (ADC) utilizing the targeting properties of antibodies and therapeutic effects of drugs have emerged a rapid development in recent years. However, the relatively low drug loading capacity of ADC systems commonly results in failure in delivering enough chemical drugs to the d...