Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia

• मुख्य लेखकों: Eunate Gallardo-Vara (लेखक), Simon Tual-Chalot (लेखक), Luisa M. Botella (लेखक), Helen M. Arthur (लेखक), Carmelo Bernabeu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2018-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Endoglin is a transmembrane glycoprotein expressed in vascular endothelium that plays a key role in angiogenesis. Mutations in the endoglin gene (ENG) cause hereditary hemorrhagic telangiectasia type 1 (HHT1), characterized by arteriovenous malformations (AVMs) in different organs. These vascular le...