Effect of elexacaftor-tezacaftor-ivacaftor on nasal potential difference and lung function in Phe508del rats

• मुख्य लेखकों: Nicole Reyne (लेखक), Patricia Cmielewski (लेखक), Alexandra McCarron (लेखक), Ronan Smith (लेखक), Elena Schneider-Futschik (लेखक), Nina Eikelis (लेखक), Piraveen Pirakalathanan (लेखक), David Parsons (लेखक), Martin Donnelley (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction:Phe508del is the most common cystic fibrosis transmembrane conductance regulator (CFTR) gene variant that results in the recessive genetic disorder cystic fibrosis (CF). The recent development of highly effective CFTR modulator therapies has led to significant health improvements in ind...