Molecular docking as a tool for the discovery of novel insight about the role of acid sphingomyelinase inhibitors in SARS- CoV-2 infectivity

• Main Authors: Samar Sami Alkafaas (Author), Abanoub Mosaad Abdallah (Author), Mai H. Hassan (Author), Aya Misbah Hussien (Author), Sara Samy Elkafas (Author), Samah A. Loutfy (Author), Abanoub Mikhail (Author), Omnia G. Murad (Author), Mohamed I. Elsalahaty (Author), Mohamed Hessien (Author), Rami M. Elshazli (Author), Fatimah A. Alsaeed (Author), Ahmed Ezzat Ahmed (Author), Hani K. Kamal (Author), Wael Hafez (Author), Mohamed T. El-Saadony (Author), Khaled A. El-Tarabily (Author), Soumya Ghosh (Author)
• Format: Book
• Published: BMC, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Recently, COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants, caused > 6 million deaths. Symptoms included respiratory strain and complications, leading to severe pneumonia. SARS-CoV-2 attaches to the ACE-2 receptor of the host cell membrane...