AKT/PACS2 Participates in Renal Vascular Hyperpermeability by Regulating Endothelial Fatty Acid Oxidation in Diabetic Mice

• Main Authors: Zhihao Shu (Author), Shuhua Chen (Author), Hong Xiang (Author), Ruoru Wu (Author), Xuewen Wang (Author), Jie Ouyang (Author), Jing Zhang (Author), Huiqin Liu (Author), Alex F. Chen (Author), Hongwei Lu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetes is a chronic metabolic disorder that can cause many microvascular and macrovascular complications, including diabetic nephropathy. Endothelial cells exhibit phenotypic and metabolic diversity and are affected by metabolic disorders. Whether changes in endothelial cell metabolism affect vasc...