High-fat-diet-induced obesity causes an inflammatory and tumor-promoting microenvironment in the rat kidney

• Main Authors: Kerstin Stemmer (Author), Diego Perez-Tilve (Author), Gayathri Ananthakrishnan (Author), Anja Bort (Author), Randy J. Seeley (Author), Matthias H. Tschöp (Author), Daniel R. Dietrich (Author), Paul T. Pfluger (Author)
• Format: Book
• Published: The Company of Biologists, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Obesity and concomitant comorbidities have emerged as public health problems of the first order. For instance, obese individuals have an increased risk for kidney cancer. However, direct mechanisms linking obesity with kidney cancer remain elusive. We hypothesized that diet-induced obesity (...