CD16 expression on monocytes in healthy individuals but not schistosome-infected patients is positively associated with levels of parasite-specific IgG and IgG1.

• Hoofdauteurs: Laura J Appleby (Auteur), Norman Nausch (Auteur), Louise Erskine (Auteur), Claire D Bourke (Auteur), Nadine Rujeni (Auteur), Nicholas Midzi (Auteur), Takafira Mduluza (Auteur), Francisca Mutapi (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2014-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Human IgG1 antibody responses are associated with protection against Schistosoma haematobium infection and are now a target for schistosome vaccine development. This study aimed to investigate the relationship between total IgG and the IgG subclasses and the monocyte IgG receptor, known as FcγRIIIa...