CD16 expression on monocytes in healthy individuals but not schistosome-infected patients is positively associated with levels of parasite-specific IgG and IgG1.

• Main Authors: Laura J Appleby (Author), Norman Nausch (Author), Louise Erskine (Author), Claire D Bourke (Author), Nadine Rujeni (Author), Nicholas Midzi (Author), Takafira Mduluza (Author), Francisca Mutapi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human IgG1 antibody responses are associated with protection against Schistosoma haematobium infection and are now a target for schistosome vaccine development. This study aimed to investigate the relationship between total IgG and the IgG subclasses and the monocyte IgG receptor, known as FcγRIIIa...