Application of ITC-Based Characterization of Thermodynamic and Kinetic Association of Ligands With Proteins in Drug Design
A comprehensive characterization of the thermodynamic and kinetic profiling of ligands binding to a given target protein is crucial for the hit selection as well as the hit-to-lead-to-drug evolution. Isothermal titration calorimetry (ITC), widely known as an invaluable tool to measure the thermodyna...
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| Main Authors: | , |
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| Format: | Book |
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Frontiers Media S.A.,
2018-10-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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