UniPR1331: Small Eph/Ephrin Antagonist Beneficial in Intestinal Inflammation by Interfering with Type-B Signaling

• Main Authors: Carmine Giorgio (Author), Marika Allodi (Author), Simone Palese (Author), Andrea Grandi (Author), Massimiliano Tognolini (Author), Riccardo Castelli (Author), Alessio Lodola (Author), Lisa Flammini (Author), Anna Maria Cantoni (Author), Elisabetta Barocelli (Author), Simona Bertoni (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Eph receptors, comprising A and B classes, interact with cell-bound ephrins generating bidirectional signaling. Although mainly related to carcinogenesis and organogenesis, the role of Eph/ephrin system in inflammation is growingly acknowledged. Recently, we showed that EphA/ephrin-A proteins can mo...