Antioxidant-Conjugated Peptide Attenuated Metabolic Reprogramming in Pulmonary Hypertension

• Main Authors: Mathews Valuparampil Varghese (Author), Maki Niihori (Author), Cody A Eccles (Author), Sergey Kurdyukov (Author), Joel James (Author), Olga Rafikova (Author), Ruslan Rafikov (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pulmonary arterial hypertension (PAH) is a chronic cardiopulmonary disorder instigated by pulmonary vascular cell proliferation. Activation of Akt was previously reported to promote vascular remodeling. Also, the irreversible nitration of Y350 residue in Akt results in its activation. NitroAkt was i...