Synthesized nano particles of glimepiride via spray freezing into cryogenic liquid: characterization, antidiabetic activity, and bioavailability

• Main Authors: Dalia A. Gaber (Author), Abdulrahman S. Alhuwaymili (Author), Hessah S. Alhawas (Author), Alhnouf A. Almutiri (Author), Amal M. Alsubaiyel (Author), Siham A. Abdoun (Author), Reem A. Almutairi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this work was to formulate glimepiride (class II drug) which is characterized by low solubility and high permeability as nanostructured particles using a cryogenic technique with an aid of water-soluble polymer to improve its aqueous solubility and hence its bioavailability. 27 formula of...