Synthesized nano particles of glimepiride via spray freezing into cryogenic liquid: characterization, antidiabetic activity, and bioavailability

• Hauptverfasser: Dalia A. Gaber (Verfasst von), Abdulrahman S. Alhuwaymili (Verfasst von), Hessah S. Alhawas (Verfasst von), Alhnouf A. Almutiri (Verfasst von), Amal M. Alsubaiyel (Verfasst von), Siham A. Abdoun (Verfasst von), Reem A. Almutairi (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The aim of this work was to formulate glimepiride (class II drug) which is characterized by low solubility and high permeability as nanostructured particles using a cryogenic technique with an aid of water-soluble polymer to improve its aqueous solubility and hence its bioavailability. 27 formula of...