Randomized, placebo‐controlled, double‐blind phase I trial of co‐administered pyronaridine and piperaquine in healthy adults of sub‐Saharan origin

• Main Authors: Andrea Kuemmerle (Author), Denis Gossen (Author), Annick Janin (Author), Andrew Stokes (Author), Nada Abla (Author), Maja Szramowska (Author), Ulrike Lorch (Author), Myriam El Gaaloul (Author), Isabelle Borghini‐Fuhrer (Author), Stephan Chalon (Author)
• Format: Book
• Published: Wiley, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Drug resistance to sulfadoxine‐pyrimethamine and amodiaquine threatens the efficacy of malaria chemoprevention interventions in children and pregnant women. Combining pyronaridine (PYR) and piperaquine (PQP), both components of approved antimalarial therapies, has the potential to protect v...