A High-Content Screen for the Identification of Plant Extracts with Insulin Secretion-Modulating Activity

• Main Authors: Roland Hager (Author), Johannes Pitsch (Author), Jakob Kerbl-Knapp (Author), Cathrina Neuhauser (Author), Nicole Ollinger (Author), Marcus Iken (Author), Josef Ranner (Author), Verena Mittermeier-Kleßinger (Author), Corinna Dawid (Author), Peter Lanzerstorfer (Author), Julian Weghuber (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bioactive plant compounds and extracts are of special interest for the development of pharmaceuticals. Here, we describe the screening of more than 1100 aqueous plant extracts and synthetic reference compounds for their ability to stimulate or inhibit insulin secretion. To quantify insulin secretion...