Exploring the multiple effects of nifedipine and captopril administration in spontaneously hypertensive rats through pharmacokinetic‐pharmacodynamic analyses
Abstract This study assessed the pharmacokinetics (PKs) and pharmacodynamics (PDs) of two antihypertensive drugs, nifedipine and captopril, by exploring their main (blood pressure [BP]) and secondary effects (heart rate [HR] and QT interval [QT]) in spontaneously hypertensive rats. This study aimed...
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Main Authors: | Akiko Kiriyama (Author), Shunsuke Kimura (Author), Shugo Yamashita (Author) |
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Format: | Book |
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Wiley,
2024-08-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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