Synthesis of New Shogaol Analogues as NRF2 Activators and Evaluation of Their Anti-Inflammatory Activity, Modes of Action and Metabolic Stability

• Main Authors: Kit-Kay Mak (Author), Zhang Shiming (Author), Raghavendra Sakirolla (Author), Madhu Katyayani Balijepalli (Author), Albena T. Dinkova-Kostova (Author), Ola Epemolu (Author), Zulkefeli Mohd (Author), Mallikarjuna Rao Pichika (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

6-shogaol is a natural and the most potent bioactive vanilloid in dried <i>Zingiber officinale</i> rhizomes. Many scientific studies have reported the diverse biological activities of 6-shogaol. However, the major drawback of 6-shogaol is its instability at room temperature. We synthesis...