In Vitro-In Vivo Relationship in Mini-Scale-Enabling Formulations of Corallopyronin A

• Main Authors: Tim Becker (Author), Anna K. Krome (Author), Sahel Vahdati (Author), Andrea Schiefer (Author), Kenneth Pfarr (Author), Alexandra Ehrens (Author), Tilman Aden (Author), Miriam Grosse (Author), Rolf Jansen (Author), Silke Alt (Author), Thomas Hesterkamp (Author), Marc Stadler (Author), Marc P. Hübner (Author), Stefan Kehraus (Author), Gabriele M. König (Author), Achim Hoerauf (Author), Karl G. Wagner (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In vivo studies in mice provide a valuable model to test novel active pharmaceutical ingredients due to their low material need and the fact that mice are frequently used as a species for early efficacy models. However, preclinical in vitro evaluations of formulation principles in mice are still lac...