Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis

• Автори: Antoni Olona (Автор), Ximena Terra (Автор), Jeong-Hun Ko (Автор), Carme Grau-Bové (Автор), Montserrat Pinent (Автор), Anna Ardevol (Автор), Ana Garcia Diaz (Автор), Aida Moreno-Moral (Автор), Matthew Edin (Автор), David Bishop-Bailey (Автор), Darryl C. Zeldin (Автор), Timothy J. Aitman (Автор), Enrico Petretto (Автор), Mayte Blay (Автор), Jacques Behmoaras (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2018-05-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Objective: When molecular drivers of healthy adipogenesis are perturbed, this can cause hepatic steatosis. The role of arachidonic acid (AA) and its downstream enzymatic cascades, such as cyclooxygenase, in adipogenesis is well established. The exact contribution of the P450 epoxygenase pathway, how...