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Manoalide Induces Intrinsic Apoptosis by Oxidative Stress and Mitochondrial Dysfunction in Human Osteosarcoma Cells

Osteosarcoma (OS) is the most common primary malignant bone tumor that produces immature osteoid. Metastatic OS has a poor prognosis with a death rate of >70%. Manoalide is a natural sesterterpenoid isolated from marine sponges. It is a phospholipase A2 inhibitor with anti-inflammatory, analgesic...

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Main Authors:	Zhi-Kang Yao (Author), Yen-Hsuan Jean (Author), Sung-Chun Lin (Author), Yu-Cheng Lai (Author), Nan-Fu Chen (Author), Chung-Chih Tseng (Author), Wu-Fu Chen (Author), Zhi-Hong Wen (Author), Hsiao-Mei Kuo (Author)
Format:	Book
Published:	MDPI AG, 2023-07-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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