Hierarchical structural component model for pathway analysis of common variants

Abstract Background Genome-wide association studies (GWAS) have been widely used to identify phenotype-related genetic variants using many statistical methods, such as logistic and linear regression. However, GWAS-identified SNPs, as identified with stringent statistical significance, explain just a...

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Main Authors: Nan Jiang (Author), Sungyoung Lee (Author), Taesung Park (Author)
Format: Book
Published: BMC, 2020-02-01T00:00:00Z.
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