Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies

• Main Authors: Jean-Paul Lasserre (Author), Alain Dautant (Author), Raeka S. Aiyar (Author), Roza Kucharczyk (Author), Annie Glatigny (Author), Déborah Tribouillard-Tanvier (Author), Joanna Rytka (Author), Marc Blondel (Author), Natalia Skoczen (Author), Pascal Reynier (Author), Laras Pitayu (Author), Agnès Rötig (Author), Agnès Delahodde (Author), Lars M. Steinmetz (Author), Geneviève Dujardin (Author), Vincent Procaccio (Author), Jean-Paul di Rago (Author)
• Format: Book
• Published: The Company of Biologists, 2015-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitochondrial diseases are severe and largely untreatable. Owing to the many essential processes carried out by mitochondria and the complex cellular systems that support these processes, these diseases are diverse, pleiotropic, and challenging to study. Much of our current understanding of mitochon...