Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions

• Үндсэн зохиолчид: Ann-Kathrin Börger (Зохиогч), Dorothee Eicke (Зохиогч), Christina Wolf (Зохиогч), Christiane Gras (Зохиогч), Susanne Aufderbeck (Зохиогч), Kai Schulze (Зохиогч), Lena Engels (Зохиогч), Britta Eiz-Vesper (Зохиогч), Axel Schambach (Зохиогч), Carlos A Guzman (Зохиогч), Nico Lachmann (Зохиогч), Thomas Moritz (Зохиогч), Ulrich Martin (Зохиогч), Rainer Blasczyk (Зохиогч), Constança Figueiredo (Зохиогч)
• Формат: Ном
• Хэвлэсэн: BMC, 2016-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Platelet (PLT) transfusion is indispensable to maintain homeostasis in thrombocytopenic patients. However, PLT transfusion refractoriness is a common life-threatening condition observed in multitransfused patients. The most frequent immune cause for PLT transfusion refractoriness is the pre...