Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions

Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions

Abstract Platelet (PLT) transfusion is indispensable to maintain homeostasis in thrombocytopenic patients. However, PLT transfusion refractoriness is a common life-threatening condition observed in multitransfused patients. The most frequent immune cause for PLT transfusion refractoriness is the pre...

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Main Authors: Ann-Kathrin Börger (Author), Dorothee Eicke (Author), Christina Wolf (Author), Christiane Gras (Author), Susanne Aufderbeck (Author), Kai Schulze (Author), Lena Engels (Author), Britta Eiz-Vesper (Author), Axel Schambach (Author), Carlos A Guzman (Author), Nico Lachmann (Author), Thomas Moritz (Author), Ulrich Martin (Author), Rainer Blasczyk (Author), Constança Figueiredo (Author)
Format: Book
Published: BMC, 2016-05-01T00:00:00Z.
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