Clinical Trial Generalizability Assessment in the Big Data Era: A Review

• Main Authors: Zhe He (Author), Xiang Tang (Author), Xi Yang (Author), Yi Guo (Author), Thomas J. George (Author), Neil Charness (Author), Kelsa Bartley Quan Hem (Author), William Hogan (Author), Jiang Bian (Author)
• Format: Book
• Published: Wiley, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Clinical studies, especially randomized, controlled trials, are essential for generating evidence for clinical practice. However, generalizability is a long‐standing concern when applying trial results to real‐world patients. Generalizability assessment is thus important, nevertheless, not...