Selective Targeting and Eradication of Various Human Non-Small Cell Lung Cancer Cell Lines Using Self-Assembled Aptamer-Decorated Nanoparticles

• Main Authors: Daniel Barak (Author), Shira Engelberg (Author), Yehuda G. Assaraf (Author), Yoav D. Livney (Author)
• Formato: Libro
• Publicado: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The leading cause of cancer mortality remains lung cancer (LC), of which non-small cell lung cancer (NSCLC) is the predominant type. Chemotherapy achieves only low response rates while inflicting serious untoward toxicity. Herein, we studied the binding and internalization of S15-aptamer (S15-APT)-d...