Gp350-anchored extracellular vesicles: promising vehicles for delivering therapeutic drugs of B cell malignancies

• Main Authors: Huiqing Xiu (Author), Xi Nan (Author), Danfeng Guo (Author), Jiaoli Wang (Author), Jiahui Li (Author), Yanmei Peng (Author), Guirun Xiong (Author), Shibo Wang (Author), Changjun Wang (Author), Gensheng Zhang (Author), Yunshan Yang (Author), Zhijian Cai (Author)
• Format: Book
• Published: Elsevier, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although chimeric antigen receptor-modified (CAR) T cell therapy has been successfully applied in the treatment of acute B lymphocytic leukemia, its effect on Burkitt lymphoma (BL) and chronic B lymphocytic leukemia (B-CLL) is unsatisfactory. Moreover, fatal side effects greatly impede CAR T cell ap...