Targeted RNA-sequencing analysis for fusion transcripts detection in tumor diagnostics: assessment of bioinformatic tools reliability in FFPE samples

• Main Authors: Iolanda Capone (Author), Fabio Bozzi (Author), Gian Paolo Dagrada (Author), Paolo Verderio (Author), Elena Conca (Author), Adele Busico (Author), Maria Adele Testi (Author), Valentina Monti (Author), Matteo Duca (Author), Claudia Proto (Author), Silvia Damian (Author), Alberta Piccolo (Author), Federica Perrone (Author), Elena Tamborini (Author), Andrea Devecchi (Author), Paola Collini (Author), Daniele Lorenzini (Author), Andrea Vingiani (Author), Luca Agnelli (Author), Giancarlo Pruneri (Author)
• Format: Book
• Published: Open Exploration Publishing Inc., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Diagnostic laboratories are progressively introducing next-generation sequencing (NGS) technologies in the routine workflow to meet the increasing clinical need for comprehensive molecular characterization in cancer patients for diagnosis and precision medicine, including fusion-transcripts det...