Method for Pulmonary Administration Using Negative Pressure Generated by Inspiration in Mice

• Prif Awduron: Yuki Oiso (Awdur), Tomomi Akita (Awdur), Daiki Kato (Awdur), Chikamasa Yamashita (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2020-02-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

When developing inhaled medicines for respiratory diseases, such as chronic obstructive pulmonary disease, drugs need to be administered by pulmonary delivery to animals in non-clinical tests. Common methods require application of pressure during administration, and it may cause lung injury, so we f...