Therapeutic inhibition of miR-155 attenuates liver fibrosis via STAT3 signaling

• Main Authors: Shashi Bala (Author), Yuan Zhuang (Author), Prashanth Thevkar Nagesh (Author), Donna Catalano (Author), Adam Zivny (Author), Yanbo Wang (Author), Jun Xie (Author), Guangping Gao (Author), Gyongyi Szabo (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Most chronic liver diseases progress to liver fibrosis, which, when left untreated, can lead to cirrhosis and hepatocellular carcinoma. MicroRNA (miRNA)-targeted therapeutics have become attractive approaches to treat diseases. In this study, we investigated the therapeutic effect of miR-155 inhibit...