Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury by modulating macrophage polarization via the SIRT1/NF-κB pathway

• Main Authors: Simeng He (Author), Xianhong Jiang (Author), Jing Yang (Author), Ya Wu (Author), Jia Shi (Author), Xiaoyang Wu (Author), Shihan Du (Author), Yuan Zhang (Author), Lirong Gong (Author), Shuan Dong (Author), Jianbo Yu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractContext Sepsis-induced acute lung injury (ALI) is a severe condition with limited effective therapeutics; nicotinamide mononucleotide (NMN) has been reported to exert anti-inflammatory activities.Objective This study explores the potential mechanisms by which NMN ameliorates sepsis-induced A...