Gentiopicroside improves non-alcoholic steatohepatitis by activating PPARα and suppressing HIF1

• Main Authors: Chaoyuan Huang (Author), Qiuhong Yong (Author), Yihui Lu (Author), Lu Wang (Author), Yiyuan Zheng (Author), Lina Zhao (Author), Peiwu Li (Author), Chong Peng (Author), Wei Jia (Author), Fengbin Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gentiopicroside (GPS) is a highly water-soluble small-molecule drug and the main bioactive secoiridoid glycoside of Gentiana scabra that has been shown to have hepatoprotective effects against non-alcoholic steatohepatitis (NASH), a form of non-alcoholic fatty liver disease (NAFLD) that can progress...