Prunella vulgaris polysaccharide inhibits herpes simplex virus infection by blocking TLR-mediated NF-κB activation

• Main Authors: Xuanlei Zhong (Author), Yibo Zhang (Author), Man Yuan (Author), Lin Xu (Author), Xiaomei Luo (Author), Rong Wu (Author), Zhichao Xi (Author), Yang Li (Author), Hongxi Xu (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Prunella vulgaris polysaccharide extracted by hot water and 30% ethanol precipitation (PVE30) was reported to possess potent antiviral effects against herpes simplex virus (HSV) infection. However, its anti-HSV mechanism has not yet been fully elucidated. Purpose This study aimed...