Lipid Nanoparticles-Encapsulated YF4: A Potential Therapeutic Oral Peptide Delivery System for Hypertension Treatment

• Main Authors: Shengnan Zhao (Author), Jinhua Li (Author), Yang Zhou (Author), Lingjing Huang (Author), Yanfei Li (Author), Juanjuan Xu (Author), Chunmei Fu (Author), Xia Guo (Author), Jian Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drugs are administered orally in the clinical treatment of hypertension. Antihypertensive peptides have excellent angiotensin converting enzyme inhibitors activity in vitro. However, the poor oral bioavailability and therapeutic effect of antihypertensive peptides were mainly caused by rapid degrada...