Overview of P-glycoprotein inhibitors: a rational outlook
P-glycoprotein (P-gp), a transmembrane permeability glycoprotein, is a member of ATP binding cassette (ABC) super family that functions specifically as a carrier mediated primary active efflux transporter. It is widely distributed throughout the body and has a diverse range of substrates. Several vi...
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Universidade de São Paulo,
2012-09-01T00:00:00Z.
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