A Survey of Strategies to Modulate the Bone Morphogenetic Protein Signaling Pathway: Current and Future Perspectives

• Principais autores: Jonathan W. Lowery (Autor), Brice Brookshire (Autor), Vicki Rosen (Autor)
• Formato: Livro
• Publicado em: Hindawi Limited, 2016-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the TGF-β family of ligands and are unequivocally involved in regulating stem cell behavior. Appropriate regulation of canonical BMP signaling is critical for the development and homeostasis of numerous human organ systems, as...