Anti-hypercholesterolemic Effects and a Good Safety Profile of SCM-198 in Animals: From ApoE Knockout Mice to Rhesus Monkeys

• Main Authors: Rinkiko Suguro (Author), Siyao Chen (Author), Di Yang (Author), Zunyuan Yang (Author), Lei Miao (Author), Weijun Wu (Author), Wen Zeng (Author), Xinhua Liu (Author), Yi Zhun Zhu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although several lipid-lowering agents have been introduced for the treatment of atherosclerosis (AS), currently marketed medications have not solved the problem completely. This study aims to investigate the effects of leonurine (SCM-198) on dyslipidemia in mammals with ApoE knockout (ApoE-/-) mice...