Therapeutic Agents with AHR Inhibiting and NRF2 Activating Activity for Managing Chloracne

Chloracne is the major skin symptom caused by dioxin intoxication. Dioxin activates the aryl hydrocarbon receptor (AHR)–cytochrome p450 1A1 (CYP1A1) system, generates oxidative stress, and induces hyperkeratinization of keratinocytes and sebocytes leading to chloracne. Nuclear factor-eryth...

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Main Authors: Masutaka Furue (Author), Yoko Fuyuno (Author), Chikage Mitoma (Author), Hiroshi Uchi (Author), Gaku Tsuji (Author)
Format: Book
Published: MDPI AG, 2018-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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