Liraglutide Enhances the Efficacy of Human Mesenchymal Stem Cells in Preserving Islet ß-cell Function in Severe Non-obese Diabetic Mice

• Main Authors: Li-rong Li (Author), Jing Lu (Author), Xiao-lei Jia (Author), Hui Hui (Author), Jie Zhang (Author), Ying Liu (Author), Wei-juan Cui (Author), Qian-yue Xu (Author), Da-long Zhu (Author)
• Format: Book
• Published: BMC, 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Glucagon-like peptide 1 (GLP-1) can promote islet β cell replication and function, and mesenchymal stem cells (MSCs) can inhibit T cell autoimmunity. The aim of this study was to test the dynamic distribution of infused human MSCs and the therapeutic effect of combined MSCs and liraglutide,...