Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies

• Autores principales: Darija Muharemagic (Autor), Anna Zamay (Autor), Shahrokh M Ghobadloo (Autor), Laura Evgin (Autor), Anna Savitskaya (Autor), John C Bell (Autor), Maxim V Berezovski (Autor)
• Formato: Libro
• Publicado: Elsevier, 2014-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Oncolytic viruses promise to significantly improve current cancer treatments through their tumor-selective replication and multimodal attack against cancer cells. However, one of the biggest setbacks for oncolytic virus therapy is the intravenous delivery of the virus, as it can be cleared from the...