Multi-Modulation of Doxorubicin Resistance in Breast Cancer Cells by Poly(<span style="font-variant: small-caps">l</span>-histidine)-Based Multifunctional Micelles

• Main Authors: Li Jia (Author), Nan Jia (Author), Yan Gao (Author), Haiyang Hu (Author), Xiuli Zhao (Author), Dawei Chen (Author), Mingxi Qiao (Author)
• Format: Book
• Published: MDPI AG, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Even though the reversal of multi-drug resistance (MDR) by numerous nanoparticles has been extensively studied, limited success has been achieved. To overcome this barrier, we report a rationally-designed pH-sensitive micelle, in which doxorubicin (Dox) and resveratrol (Res) were co-loaded. The mice...