Physiologically Based Pharmacokinetic Modelling of UGT Substrate Drugs Lamotrigine and Raltegravir during Pregnancy

• Hoofdauteurs: Monika Berezowska (Auteur), Paola Coppola (Auteur), Venkatesh Pilla Reddy (Auteur), Pradeep Sharma (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2024-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Pregnancy is associated with various physiological changes that can significantly impact the disposition of drugs. To further the insight into how pregnancy affects the pharmacokinetics of drugs at different stages, clinical studies can be simulated using Physiologically Based Pharmacokinetic modell...