Physiologically Based Pharmacokinetic Modelling of UGT Substrate Drugs Lamotrigine and Raltegravir during Pregnancy

• मुख्य लेखकों: Monika Berezowska (लेखक), Paola Coppola (लेखक), Venkatesh Pilla Reddy (लेखक), Pradeep Sharma (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2024-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Pregnancy is associated with various physiological changes that can significantly impact the disposition of drugs. To further the insight into how pregnancy affects the pharmacokinetics of drugs at different stages, clinical studies can be simulated using Physiologically Based Pharmacokinetic modell...