Refinement and calibration of a human PBPK model for the plasticiser, Di-(2-propylheptyl) phthalate (DPHP) using in silico, in vitro and human biomonitoring data

An existing physiologically based pharmacokinetic model for Di-(2-propylheptyl) phthalate (DPHP) was refined to improve the simulations of the venous blood concentrations of the primary monoester metabolite, mono-(2-propylheptyl) phthalate (MPHP). This was considered a significant deficiency that sh...

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Main Authors: Kevin McNally (Author), George Loizou (Author)
Format: Book
Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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