Tuning the Biological Activity of Camphorimine Complexes through Metal Selection

• Auteurs principaux: Joana P. Costa (Auteur), Teresa Pinheiro (Auteur), Maria S. Martins (Auteur), M. Fernanda N. N. Carvalho (Auteur), Joana R. Feliciano (Auteur), Jorge H. Leitão (Auteur), Rafaela A. L. Silva (Auteur), Joana F. Guerreiro (Auteur), Luís M. C. Alves (Auteur), Inês Custódio (Auteur), João Cruz (Auteur), Fernanda Marques (Auteur)
• Format: Livre
• Publié: MDPI AG, 2022-07-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The cytotoxic activity of four sets of camphorimine complexes based on the Cu(I), Cu(II), Ag(I), and Au(I) metal sites were assessed against the cisplatin-sensitive A2780 and OVCAR3 ovarian cancer cells. The results showed that the gold complexes were ca. one order of magnitude more active than the...