Simultaneous targeting therapy for lung metastasis and breast tumor by blocking the NF-κB signaling pathway using Celastrol-loaded micelles

• Main Authors: Yue Zhao (Author), Yanan Tan (Author), Tingting Meng (Author), Xuan Liu (Author), Yun Zhu (Author), Yun Hong (Author), Xiqin Yang (Author), Hong Yuan (Author), Xuan Huang (Author), Fuqiang Hu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metastasis is one of the major obstacles for successful therapy of breast tumor. To inhibit the metastasis and growth of breast tumor simultaneously, a Celastrol (Cela) loaded glucolipid-like conjugates (CSOSA/Cela) with αvβ3-ligand Tetraiodothyroacetic acid (TET) modification (TET-CSOSA/Cela) were...