Blockade of IL-17A/IL-17R Pathway Protected Mice from Sepsis-Associated Encephalopathy by Inhibition of Microglia Activation

• Váldodahkkit: Bo Ye (Dahkki), Tianzhu Tao (Dahkki), Andong Zhao (Dahkki), Liyuan Wen (Dahkki), Xiaofei He (Dahkki), Yi Liu (Dahkki), Qiang Fu (Dahkki), Weidong Mi (Dahkki), Jingsheng Lou (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2019-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Sepsis-associated encephalopathy (SAE) is a poorly understood condition that leads to long-term cognitive impairment and increased mortality in survivors. Recent research revealed that IL-17A/IL-17R might serve as a checkpoint in microglia-mediated neuroinflammation. The present study was designed t...