Radiotherapy Suppresses Bone Cancer Pain through Inhibiting Activation of cAMP Signaling in Rat Dorsal Root Ganglion and Spinal Cord

• Main Authors: Guiqin Zhu (Author), Yanbin Dong (Author), Xueming He (Author), Ping Zhao (Author), Aixing Yang (Author), Rubing Zhou (Author), Jianhua Ma (Author), Zhong Xie (Author), Xue-Jun Song (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiotherapy is one of the major clinical approaches for treatment of bone cancer pain. Activation of cAMP-PKA signaling pathway plays important roles in bone cancer pain. Here, we examined the effects of radiotherapy on bone cancer pain and accompanying abnormal activation of cAMP-PKA signaling. Fe...