Copy-number variation in <it>BMPR2 </it>is not associated with the pathogenesis of pulmonary arterial hypertension

• Autori principali: Cogan Joy D (Autore), Vnencak-Jones Cindy L (Autore), Johnson Jennifer A (Autore), Loyd James E (Autore), West James (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2009-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Copy-number variations (CNVs) are structural variations in the genome involving 1 kb to 3 mb of DNA. CNV has been reported within intron 1 of the <it>BMPR2 </it>gene. We propose that CNV could affect phenotype in familial...