Actin alpha 2, smooth muscle, a transforming growth factor-β1-induced factor, regulates collagen production in human periodontal ligament cells via Smad2/3 pathway

• Main Authors: Naati Fakatava (Author), Hiromi Mitarai (Author), Asuka Yuda (Author), Akira Haraguchi (Author), Hiroko Wada (Author), Daigaku Hasegawa (Author), Hidefumi Maeda (Author), Naohisa Wada (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Actin alpha 2, smooth muscle (ACTA2) is an actin isoform that forms the cytoskeleton. Actin plays a crucial role in numerous cellular functions. ACTA2 is a marker of functional periodontal ligament (PDL) fibroblasts and is upregulated by transforming growth factor-β1 (TGF-β1); ho...