PSAT1 is upregulated by METTL3 to attenuate high glucose-induced retinal pigment epithelial cell apoptosis and oxidative stress

• Päätekijät: Xiaofeng Du (Tekijä), Yanting Wang (Tekijä), Fan Gao (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2024-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background Diabetic retinopathy (DR) is a major ocular complication of diabetes mellitus, and a significant cause of visual impairment and blindness in adults. Phosphoserine aminotransferase 1 (PSAT1) is an enzyme participating in serine synthesis, which might improve insulin signaling and...