RANKL blockade alleviates peri-implant bone loss and is enhanced by anti-inflammatory microRNA-146a through TLR2/4 signaling

• Main Authors: Keqing Pan (Author), Yang Hu (Author), Yufeng Wang (Author), Hao Li (Author), Michele Patel (Author), Danyang Wang (Author), Zuomin Wang (Author), Xiaozhe Han (Author)
• Formato: Livro
• Publicado em: SpringerOpen, 2020-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background The present study was to determine the effect of local anti-RANKL antibody administration in the presence or absence of microRNA-146a on ligature-induced peri-implant bone resorption, and the potential role of TLR2/4 signaling in such effect. Results Titanium implants were placed...